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Anti-SLC3A2 antibody produced in rabbit

SIGMA/SAB1400262 - IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-4F2; Anti-4F2HC; Anti-4T2HC; Anti-CD98; Anti-CD98HC; Anti-MDU1; Anti-NACAE

MDL Number: MFCD03455856
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SAB1400262-100UG 100 µg
$580.00
1/EA
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Western Blotting SLC3A2 rabbit polyclonal antibody. Western Blot analysis of SLC3A2 expression in A-431.
Western Blotting Western Blot analysis of SLC3A2 expression in transfected 293T cell line by SLC3A2 polyclonal antibody. Lanes Lane 1: SLC3A2 transfected lysate (57.90 kDa). Lane 2: Non-transfected lysate.
Western Blotting SLC3A2 rabbit polyclonal antibody. Western Blot analysis of SLC3A2 expression in mouse brain.
Western Blotting SLC3A2 rabbit polyclonal antibody. Western Blot analysis of SLC3A2 expression in mouse kidney.
Western Blotting SLC3A2 rabbit polyclonal antibody. Western Blot analysis of SLC3A2 expression in rat brain.

 

antibody form IgG fraction of antiserum
antibody product type primary antibodies
biological source rabbit
clone polyclonal
conjugate unconjugated
form buffered aqueous solution
Quality Level 100 
shipped in dry ice
species reactivity mouse, human
storage temp. −20°C
target post-translational modification unmodified
technique(s) western blot: 1 μg/mL
UniProt accession no. P08195 
Biochem/physiol Actions: Solute carrier family 3 member 2 (SLC3A2) has a role in amino acid transport. It associates with integrins and modulates their signaling functions. The protein is involved in cell-to-cell fusion occurring between macrophages or trophoblasts. SLC3A2 is overexpressed in various cancers.
Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description: This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. It associates with integrins and mediates integrin-dependent signaling related to normal cell growth and tumorigenesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. (provided by RefSeq)
Solute carrier family 3 member 2 (SLC3A2) is a type II transmembrane glycoprotein which is widely expressed. It is expressed on the cell membrane and in some types of endosomes. The protein is part of the heterodimeric amino acid transporter family. The SLC3A2 gene is localized on human chromosome 11q13.
Immunogen: SLC3A2 (NP_001013269.1, 1 a.a. ~ 529 a.a) full-length human protein.

Sequence
MSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFSTQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR NONH for all modes of transport
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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