Anti-APEX2 antibody produced in mouse
SIGMA/SAB1400507 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-APE2; Anti-APEXL2; Anti-XTH2
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to APEX2 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of APEX2 expression in transfected 293T cell line by APEX2 polyclonal antibody. Lanes Lane 1: APEX2 transfected lysate (56.98 kDa). Lane 2: Non-transfected lysate.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q9UBZ4  |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). (provided by RefSeq) |
| Immunogen: | APEX2 (NP_055296.2, 1 a.a. ~ 518 a.a) full-length human protein. Sequence MLRVVSWNINGIRRPLQGVANQEPS |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |