Anti-A1CF antibody produced in mouse
SIGMA/SAB1400523 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-ACF; Anti-ACF64; Anti-ACF65; Anti-APOBEC1CF; Anti-ASP; Anti-MGC163391; Anti-RP11-564C4.2
MDL Number: MFCD09753847
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to A1CF on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of A1CF expression in transfected 293T cell line by A1CF polyclonal antibody. Lanes Lane 1: ACF transfected lysate (65.34 kDa). Lane 2: Non-transfected lysate.
Western Blotting ACF polyclonal antibody. Western Blot analysis of ACF expression in human placenta.
Western Blotting A1CF polyclonal antibody. Western Blot analysis of A1CF expression in HeLa.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q9NQ94  |
| General description: | Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined. (provided by RefSeq) |
| Immunogen: | A1CF (NP_620311.1, 1 a.a. ~ 594 a.a) full-length human protein. Sequence MEAVCLGTCPEPEASMSTAIPGLKK |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |