Anti-CYP2A6 antibody produced in rabbit
SIGMA/SAB1401103 - purified immunoglobulin, buffered aqueous solution
Synonym: CPA6; CYP2A; CYP2A3; P450C2A; P450PB
Product Type: Chemical
Western Blotting CYP2A6 rabbit polyclonal antibody. Western Blot analysis of CYP2A6 expression in human liver.
Western Blotting Western Blot analysis of CYP2A6 expression in transfected 293T cell line by CYP2A6 polyclonal antibody. Lanes Lane 1: CYP2A6 transfected lysate (56.50 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | BC096255.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P11509 |
| General description: | This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. (provided by RefSeq) |
| Immunogen: | CYP2A6 (AAH96255.1, 1 a.a. ~ 494 a.a) full-length human protein. Sequence MLASGMLLVALLVCLTVMVLMSVWQ |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |