Anti-MS4A2 antibody produced in rabbit
SIGMA/SAB1401132 - purified immunoglobulin, buffered aqueous solution
Synonym: APY; ATOPY; FCER1B; FCERI; IGEL; IGER
MDL Number: MFCD00211769
Product Type: Chemical
Western Blotting Western Blot analysis of MS4A2 expression in transfected 293T cell line by MS4A2 polyclonal antibody. Lanes Lane 1: MS4A2 transfected lysate (26.50 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NM_000139   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q01362 |
| General description: | The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. Alternative splicing results in multiple transcript variants encoding different isoforms |
| Immunogen: | MS4A2 (NP_000130.1, 1 a.a. ~ 244 a.a) full-length human protein. Sequence MDTESNRRANLALPQEPSSVPAFEV |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |