Anti-HLA-DOB antibody produced in rabbit
SIGMA/SAB1401176 - purified immunoglobulin, buffered aqueous solution
Synonym: DOB
Product Type: Chemical
Western Blotting Western Blot analysis of HLA-DOB expression in transfected 293T cell line by HLA-DOB polyclonal antibody. Lanes Lane 1: HLA-DOB transfected lysate (30.80 kDa). Lane 2: Non-transfected lysate.
Western Blotting HLA-DOB rabbit polyclonal antibody. Western Blot analysis of HLA-DOB expression in human placenta.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NM_002120   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P13765 |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. (provided by RefSeq) |
| Immunogen: | HLA-DOB (NP_002111.1, 1 a.a. ~ 273 a.a) full-length human protein. Sequence MGSGWVPWVVALLVNLTRLDSSMTQ |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |