Anti-POLH antibody produced in mouse
SIGMA/SAB1401290 - purified immunoglobulin, buffered aqueous solution
Synonym: FLJ16395; FLJ21978; RAD30; RAD30A; XP-V; XPV
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to POLH on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of POLH expression in transfected 293T cell line by POLH polyclonal antibody. Lanes Lane 1: POLH transfected lysate (78.43 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NM_006502.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | direct immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q9Y253 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. (provided by RefSeq) |
| Immunogen: | POLH (NP_006493.1, 1 a.a. ~ 713 a.a) full-length human protein. Sequence MATGQDRVVALVDMDCFFVQVEQRQ |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |