Anti-PRLR antibody produced in rabbit
SIGMA/SAB1401312 - purified immunoglobulin, buffered aqueous solution
Synonym: hPRLrI
MDL Number: MFCD07370459
Product Type: Chemical
Western Blotting PRLR rabbit polyclonal antibody. Western Blot analysis of PRLR expression in A-431.
Western Blotting Western Blot analysis of PRLR expression in transfected 293T cell line by PRLR polyclonal antibody. Lanes Lane 1: PRLR transfected lysate (69.50 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NM_000949   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P16471 |
| Biochem/physiol Actions: | Deletion of PRLR (prolactin receptor) leads to development of prolactinomas in mice. Mutation in the gene is known to cause familial hyperprolactinemia. Overexpression of PRLR might be associated with tumorigenesis of cervical cancer. The gene is known to be downregulated in invasive breast cancer metastasis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | PRLR (NP_000940.1, 1 a.a. ~ 622 a.a) full-length human protein. Sequence MKENVASATVFTLLLFLNTCLLNGQ |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |