Anti-TFAM antibody produced in rabbit
SIGMA/SAB1401383 - purified immunoglobulin, buffered aqueous solution
Synonym: MtTF1; TCF6; TCF6L1; TCF6L2; TCF6L3; mtTFA
Product Type: Chemical
Western Blotting Western Blot analysis of TFAM expression in transfected 293T cell line by TFAM polyclonal antibody. Lanes Lane 1: TFAM transfected lysate (29.10 kDa). Lane 2: Non-transfected lysate.
Western Blotting TFAM rabbit polyclonal antibody. Western Blot analysis of TFAM expression in mouse liver.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NM_003201.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q00059 |
| Application: | Anti-TFAM antibody produced in rabbit has been used in western blotting (1:1000) and immunofluorescence. |
| Biochem/physiol Actions: | Mitochondrial transcription factor A (TFAM) is involved in mitochondrial DNA (mtDNA) synthesis, expression, and packaging. It is also involved in regulating the aggregation of mtDNA. TFAM stabilizes the mtDNA by binding to it in a sequence-depending manner and forms a nucleoid. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Mitochondrial transcription factor A (TFAM) is a high-mobility group (HMG) protein and is made up of two HMG-box domains. The TFAM gene is located on the human chromosome at 10q21.1. |
| Immunogen: | TFAM (NP_003192.1, 1 a.a. ~ 246 a.a) full-length human protein. Sequence MAFLRSMWGVLSALGRSGAELCTGC |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |