Anti-AHI1 antibody produced in rabbit
SIGMA/SAB1401732 - purified immunoglobulin, buffered aqueous solution
Synonym: AHI-1; DKFZp686J1653; FLJ14023; FLJ20069; JBTS3; ORF1
Product Type: Chemical
Western Blotting Western Blot analysis of AHI1 expression in transfected 293T cell line by AHI1 polyclonal antibody. Lanes Lane 1: AHI1 transfected lysate (70.00 kDa). Lane 2: Non-transfected lysate.
Western Blotting AHI1 rabbit polyclonal antibody. Western Blot analysis of AHI1 expression in mouse testis.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | BC094800.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q8N157 |
| Biochem/physiol Actions: | The AHI1 (Abelson helper integration site 1) protein is responsible for the cerebellar and cortical structure growth during embryonic development. Mutation in AHI1 (Abelson helper integration site 1) might result in schizophrenia, a mental disorder that is highly heritable. AHI1 variants cause oculomotor apraxia, leading to Joubert syndrome-related disorders. The encoded protein is associated with canonical Wnt signaling. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
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| General description: | This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq) |
| Immunogen: | AHI1 (AAH94800.1, 1 a.a. ~ 609 a.a) full-length human protein. Sequence MPTAESEAKVKTKVRFEELLKTHSD |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |