Anti-ELAC2 antibody produced in mouse
SIGMA/SAB1401791 - purified immunoglobulin, buffered aqueous solution
Synonym: ELC2; FLJ10530; FLJ36693; FLJ42848; HPC2
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to ELAC2 on HepG2 cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of ELAC2 expression in transfected 293T cell line by ELAC2 polyclonal antibody. Lanes Lane 1: ELAC2 transfected lysate (90.86 kDa). Lane 2: Non-transfected lysate.
Western Blotting ELAC2 polyclonal antibody. Western Blot analysis of ELAC2 expression in Jurkat.
Western Blotting ELAC2 polyclonal antibody. Western Blot analysis of ELAC2 expression in COLO 320 HSR.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NM_018127.4   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | direct immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q9BQ52 |
| General description: | The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) |
| Immunogen: | ELAC2 (NP_060597.3, 1 a.a. ~ 826 a.a) full-length human protein. Sequence MWALCSLLRSAAGRTMSQGRTISQA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |