Anti-KREMEN2 antibody produced in mouse
SIGMA/SAB1401822 - purified immunoglobulin, buffered aqueous solution
Synonym: KRM2; MGC10791; MGC16709
Product Type: Chemical
Western Blotting Western Blot analysis of KREMEN2 expression in transfected 293T cell line by KREMEN2 polyclonal antibody. Lane1:KREMEN2 transfected lysate (46.2 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NM_024507   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q8NCW0 |
| General description: | This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. (provided by RefSeq) |
| Immunogen: | KREMEN2 (NP_078783.1, 1 a.a. ~ 420 a.a) full-length human protein. Sequence MGTQALQGFLFLLFLPLLQPRGASA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |