Monoclonal Anti-SPANXB1 antibody produced in mouse
SIGMA/SAB1402101 - clone 2E12, ascites fluid
Synonym: B1; SPANX-B; SPANXB
Product Type: Chemical
Immunoblotting Monoclonal Anti-SPANXB1, antibody produced in mouse, clone 2E12, ascites fluid: Cat. No. SAB1402101: Antibody concentration: 1.0 μg/mL. Specific band of ~37.44 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (37.07 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2E12, monoclonal |
| conjugate | unconjugated |
| isotype | IgMκ |
| NCBI accession no. | BC034472   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | capture ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9NS25 |
| General description: | Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. (provided by RefSeq) |
| Immunogen: | SPANXB1 (AAH34472, 1 a.a. ~ 103 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MGQQSSVRRLKRSVPCESNEANEAN |
| Physical form: | Clear solution |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |