Monoclonal Anti-MMP3 antibody produced in mouse
SIGMA/SAB1402273 - clone 4C11, purified immunoglobulin, buffered aqueous solution
Synonym: CHDS6; MGC126102; MGC126103; MGC126104; MMP-3; SL-1; STMY; STMY1; STR1
MDL Number: MFCD03455413
Product Type: Chemical
Immunoprecipitation Immunoprecipitation of MMP3 transfected lysate using anti-MMP3 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with MMP3 rabbit polyclonal antibody.
ELISA Detection limit for recombinant GST tagged MMP3 is 0.1 ng/mL as a capture antibody.
ELISA Detection limit for recombinant GST tagged MMP3 is approximately 3 ng/mL as a capture antibody.
ELISA Detection limit for recombinant GST tagged MMP3 is 1 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4C11, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2bκ |
| mol wt | antigen ~38.21 kDa |
| NCBI accession no. | NM_002422   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | capture ELISA: suitable |
| immunoprecipitation (IP): suitable | |
| indirect ELISA: suitable | |
| UniProt accession no. | P08254 |
| General description: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. (provided by RefSeq) |
| Immunogen: | MMP3 (NP_002413, 22 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence GAARGEDTSMNLVQKYLENYYDLKK |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |