Monoclonal Anti-ACACB antibody produced in mouse
SIGMA/SAB1402679 - clone 1C11, ascites fluid
Synonym: ACC2; ACCB; HACC275
Product Type: Chemical
Immunoblotting Monoclonal Anti-ACACB: Cat. No. SAB1402679: Antibody concentration: 1 μg/mL. Specific band of ~37 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (36.63 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1C11, monoclonal |
| conjugate | unconjugated |
| isotype | IgMκ |
| mol wt | antigen ~37 kDa |
| NCBI accession no. | NM_001093   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | O00763 |
| General description: | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. (provided by RefSeq) |
| Immunogen: | ACACB (NP_001084, 22 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence IWGKMTDSKPITKSKSEANLIPSQE |
| Physical form: | Clear solution |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |