Monoclonal Anti-PRELP antibody produced in mouse
SIGMA/SAB1402879 - clone 3H1, ascites fluid
Synonym: MGC45323; MST161; MSTP161; SLRR2A
Product Type: Chemical
Immunoblotting Monoclonal Anti-PRELP: Cat. No. SAB1402879: Antibody concentration: 1 μg/mL. Specific band of ~35.5 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (35.09 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3H1, monoclonal |
| conjugate | unconjugated |
| isotype | IgMκ |
| mol wt | antigen ~35.46 kDa |
| NCBI accession no. | NM_002725   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P51888 |
| General description: | The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. (provided by RefSeq) |
| Immunogen: | PRELP (NP_002716.1, 281 a.a. ~ 365 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence RGLPKNSFNISNLLVLHLSHNRISS |
| Physical form: | Clear solution |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |