Monoclonal Anti-KLF2 antibody produced in mouse
SIGMA/SAB1403063 - clone 1D1, purified immunoglobulin, buffered aqueous solution
Synonym: LKLF
Product Type: Chemical
Immunoblotting Monoclonal Anti-KLF2: Cat. No. SAB1403063: Antibody concentration: 1 μg/mL. Specific band of ~35.5 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (35.42 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1D1, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen ~35.79 kDa |
| NCBI accession no. | NM_016270   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9Y5W3 |
| Biochem/physiol Actions: | Kruppel like factor 2 (KLF2) is crucial for lung functioning, cell differentiation, migration and tissue development. It modulates endothelial pro-inflammatory activation. The protein has roles in cardiovascular development and T-cell differentiation. Mutation in the gene encoding it has been associated with heritable pulmonary arterial hypertension. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Kruppel like factor 2 (KLF2) is a tumor-suppressor gene, localized on human chromosome 19p13.11. |
| Immunogen: | KLF2 (NP_057354, 263 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence SWPRKRTATHTCSYAGCGKTYTKSS |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |