Monoclonal Anti-SERPINC1 antibody produced in mouse
SIGMA/SAB1403580 - clone 2B12, ascites fluid
Synonym: AT3; ATIII; MGC22579
Product Type: Chemical
Western Blotting Western Blot analysis of SERPINC1 expression in transfected 293T cell line by SERPINC1 monoclonal antibody, clone 2B12. Lanes Lane 1: SERPINC1 transfected lysate (29.1 kDa). Lane 2: Non-transfected lysate.
Western Blotting SERPINC1 monoclonal antibody, clone 2B12. Western Blot analysis of SERPINC1 expression in human kidney.
Western Blotting QC Western Blot detection against Immunogen (54.23 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2B12, monoclonal |
| conjugate | unconjugated |
| isotype | IgG2bκ |
| mol wt | antigen ~54.6 kDa |
| NCBI accession no. | BC022309   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P01008 |
| General description: | The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. (provided by RefSeq) |
| Immunogen: | SERPINC1 (AAH22309.1, 1 a.a. ~ 259 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MYSNVIGTVTSGKRKVYLLSLLLIG |
| Physical form: | Clear solution |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |