Monoclonal Anti-SKP1A, (C-terminal) antibody produced in mouse
SIGMA/SAB1404372 - clone 2E6, purified immunoglobulin, buffered aqueous solution
Synonym: EMC19; MGC34403; OCP-II; OCP2; SKP1A; TCEB1L; p19A
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to SKP1 on HeLa cell. [antibody concentration 30 μg/mL]
Western Blotting SKP1A monoclonal antibody, clone 2E6. Western Blot analysis of SKP1A expression in HeLa.
Western Blotting QC Western Blot detection against Immunogen (37.62 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2E6, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen ~37.99 kDa |
| NCBI accession no. | NM_006930   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| indirect ELISA: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | P63208 |
| General description: | This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. (provided by RefSeq) |
| Immunogen: | SKP1A (NP_008861, 53 a.a. ~ 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence AILKKVIQWCTHHKDDPPPPEDDEN |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |