Monoclonal Anti-CXCR4, (N-terminal) antibody produced in mouse
SIGMA/SAB1404560 - clone 2G9, purified immunoglobulin, buffered aqueous solution
Synonym: CD184; D2S201E; FB22; HM89; HSY3RR; LAP3; LCR1; LESTR; NPY3R
Product Type: Chemical
Western Blotting Western Blot analysis of CXCR4 expression in transfected 293T cell line by CXCR4 monoclonal antibody, clone 2G9. Lanes Lane 1: CXCR4 transfected lysate (Predicted MW: 39.7 kDa). Lane 2: Non-transfected lysate.
Western Blotting CXCR4 monoclonal antibody, clone 2G9. Western Blot analysis of CXCR4 expression in human colon.
Western Blotting CXCR4 monoclonal antibody, clone 2G9. Western Blot analysis of CXCR4 expression in human intestinal wall.
Western Blotting CXCR4 monoclonal antibody, clone 2G9. Western Blot analysis of CXCR4 expression in RIN-m5F.
Western Blotting QC Western Blot detection against Immunogen (30.8 kDa).
ELISA Detection limit for recombinant GST tagged CXCR4 is 0.03 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2G9, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen ~31.17 kDa |
| NCBI accession no. | BC020968   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | capture ELISA: suitable |
| ELISA: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | P61073 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. (provided by RefSeq) |
| Immunogen: | CXCR4 (AAH20968, 1 a.a. ~ 46 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MEGISIYTSDNYTEEMGSGDYDSMK |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |