Monoclonal Anti-UBR2, (N-terminal) antibody produced in mouse
SIGMA/SAB1404963 - clone 4G4, ascites fluid
Synonym: C6orf133; DKFZp686C08114; KIAA0349; MGC71112; RP3-392M17.3; bA49A4.1; dJ242G1.1; dJ392M17.3
Product Type: Chemical
Western Blotting Western Blot analysis of UBR2 expression in transfected 293T cell line by UBR2 monoclonal antibody, clone 4G4. Lanes Lane 1: UBR2 transfected lysate (50 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (36.74 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4G4, monoclonal |
| conjugate | unconjugated |
| isotype | IgG2aκ |
| mol wt | antigen ~37.11 kDa |
| NCBI accession no. | NM_015255   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q8IWV8 |
| General description: | Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate′s destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM |
| Immunogen: | UBR2 (NP_056070, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MASELEPEVQAIDRSLLECSAEEIA |
| Physical form: | Clear solution |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |