Monoclonal Anti-ACD antibody produced in mouse
SIGMA/SAB1405257 - clone 1C11-1A7, purified immunoglobulin, buffered aqueous solution
Synonym: PIP1; PTOP; TINT1; TPP1
Product Type: Chemical
Western Blotting Western Blot analysis of ACD expression in transfected 293T cell line by ACD monoclonal antibody, clone 1C11-1A7. Lanes Lane 1: ACD transfected lysate (Predicted MW: 57.7 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (85.58 kDa).
Immunoprecipitation Immunoprecipitation of ACD transfected lysate using anti-ACD monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with ACD rabbit polyclonal antibody.
ELISA Detection limit for recombinant GST tagged ACD is 1 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1C11-1A7, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG1κ |
| mol wt | antigen ~85.95 kDa |
| NCBI accession no. | BC016904   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoprecipitation (IP): suitable |
| indirect ELISA: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q96AP0 |
| General description: | This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. (provided by RefSeq) |
| Immunogen: | ACD (AAH16904, 1 a.a. ~ 544 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MPGRCQSDAAMRVNGPASRAPAGWT |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |