Anti-BCKDHA antibody produced in mouse
SIGMA/SAB1405509 - purified immunoglobulin, buffered aqueous solution
Synonym: BCKDE1A; FLJ45695; MSU; MSUD1; OVD1A
Product Type: Chemical
Western Blotting Western Blot analysis of BCKDHA expression in transfected 293T cell line by BCKDHA polyclonal antibody. Lanes Lane 1: BCKDHA transfected lysate (48.95 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~50.5 kDa |
| NCBI accession no. | NM_000709.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P12694 |
| General description: | The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene |
| Immunogen: | BCKDHA (NP_000700.1, 1 a.a. ~ 445 a.a) full-length human protein. Sequence MAVAIAAARVWRLNRGLSQAALLLL |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |