Anti-CBFA2T3 antibody produced in mouse
SIGMA/SAB1405563 - purified immunoglobulin, buffered aqueous solution
Synonym: ETO2; MTG16; MTGR2; ZMYND4
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of antibody to CBFA2T3 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 μg/mL]
Western Blotting Western Blot analysis of CBFA2T3 expression in transfected 293T cell line by CBFA2T3 polyclonal antibody. Lanes Lane 1: CBFA2T3 transfected lysate (67.65 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~66.9 kDa |
| NCBI accession no. | BC062624.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | O75081 |
| General description: | The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5′-region of the AML1 gene fused to the 3′-region of this gene. In addition, this gene is a putative breast tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene, and a brefeldin A-sensitive association of RII-alpha protein with one of the isoforms has been demonstrated in the Golgi apparatus. (provided by RefSeq) |
| Immunogen: | CBFA2T3 (AAH62624.1, 1 a.a. ~ 615 a.a) full-length human protein. Sequence MPASRLRDRAASSASGSTCGSMSQT |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |