Anti-CCND2 antibody produced in mouse
SIGMA/SAB1405571 - purified immunoglobulin, buffered aqueous solution
Synonym: KIAK0002; MGC102758
Product Type: Chemical
Western Blotting CCND2 polyclonal antibody. Western Blot analysis of CCND2 expression in human placenta.
Western Blotting Western Blot analysis of CCND2 expression in transfected 293T cell line by CCND2 polyclonal antibody. Lanes Lane 1: CCND2 transfected lysate (31.79 kDa). Lane 2: Non-transfected lysate.
Western Blotting CCND2 polyclonal antibody. Western Blot analysis of CCND2 expression in A-431.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~33.1 kDa |
| NCBI accession no. | NM_001759   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P30279 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. (provided by RefSeq) |
| Immunogen: | CCND2 (NP_001750.1, 1 a.a. ~ 289 a.a) full-length human protein. Sequence MELLCHEVDPVRRAVRDRNLLRDDR |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |