Anti-CCNH antibody produced in mouse
SIGMA/SAB1405573 - purified immunoglobulin, buffered aqueous solution
Synonym: CAK; p34; p37
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to CCNH on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting CCNH polyclonal antibody. Western Blot analysis of CCNH expression in human kidney.
Western Blotting Western Blot analysis of CCNH expression in transfected 293T cell line by CCNH polyclonal antibody. Lanes Lane 1: CCNH transfected lysate (35.53 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~37.6 kDa |
| NCBI accession no. | NM_001239   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | P51946 |
| General description: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. (provided by RefSeq) |
| Immunogen: | CCNH (NP_001230.1, 1 a.a. ~ 323 a.a) full-length human protein. Sequence MYHNSSQKRHWTFSSEEQLARLRAD |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |