Anti-CD8B antibody produced in mouse
SIGMA/SAB1405578 - purified immunoglobulin, buffered aqueous solution
Synonym: CD8B1; LYT3; Leu2; Ly3; MGC119115
Product Type: Chemical
Western Blotting Western Blot analysis of CD8B expression in transfected 293T cell line by CD8B polyclonal antibody. Lanes Lane 1: CD8B1 transfected lysate (26.73 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~27.2 kDa |
| NCBI accession no. | NM_172213   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P10966 |
| General description: | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. (provided by RefSeq) |
| Immunogen: | CD8B (NP_757362.1, 1 a.a. ~ 243 a.a) full-length human protein. Sequence MRPRLWLLLAAQLTVLHGNSVLQQT |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |