Anti-CDKN2B antibody produced in mouse
SIGMA/SAB1405602 - purified immunoglobulin, buffered aqueous solution
Synonym: CDK4I; INK4B; MTS2; P15; TP15; p15INK4b
Product Type: Chemical
Western Blotting Western Blot analysis of CDKN2B expression in transfected 293T cell line by CDKN2B polyclonal antibody. Lanes Lane 1: CDKN2B transfected lysate (15.29 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~15.29 kDa |
| NCBI accession no. | BC014469   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P42772 |
| General description: | This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. (provided by RefSeq) |
| Immunogen: | CDKN2B (AAH14469, 1 a.a. ~ 138 a.a) full-length human protein. Sequence MREENKGIPSGGGSDEGLASAAARG |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |