Anti-DDB1 antibody produced in mouse
SIGMA/SAB1405702 - purified immunoglobulin, buffered aqueous solution
Synonym: DDBA; UV-DDB1; XAP1; XPCE; XPE; XPE-BF
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to DDB1 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of DDB1 expression in transfected 293T cell line by DDB1 polyclonal antibody. Lanes Lane 1: DDB1 transfected lysate (127.00 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~127 kDa |
| NCBI accession no. | XM_001128983.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q16531 |
| General description: | This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. (provided by RefSeq) |
| Immunogen: | DDB1 (XP_001128983.1, 1 a.a. ~ 1140 a.a) full-length human protein. Sequence MSYNYVVTAQKPTAVNGCVTGHFTS |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |