Anti-HLA-DPA1 antibody produced in mouse
SIGMA/SAB1405941 - purified immunoglobulin, buffered aqueous solution
Synonym: HLA-DP1A; HLADP; HLASB
Product Type: Chemical
Western Blotting Western Blot analysis of HLA-DPA1 expression in transfected 293T cell line by HLA-DPA1 polyclonal antibody. Lanes Lane 1: HLA-DPA1 transfected lysate (28.6 kDa). Lane 2: Non-transfected lysate.
Western Blotting HLA-DPA1 polyclonal antibody. Western Blot analysis of HLA-DPA1 expression in human spleen.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~29.3 kDa |
| NCBI accession no. | BC009956   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P20036 |
| General description: | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. (provided by RefSeq) |
| Immunogen: | HLA-DPA1 (AAH09956.1, 1 a.a. ~ 260 a.a) full-length human protein. Sequence MRPEDRMFHIRAVILRALSLAFLLS |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |