Anti-IL5RA antibody produced in mouse
SIGMA/SAB1406024 - purified immunoglobulin, buffered aqueous solution
Synonym: CD125; CDw125; HSIL5R3; IL5R; MGC26560
Product Type: Chemical
Western Blotting Western Blot analysis of IL5RA expression in transfected 293T cell line by IL5RA polyclonal antibody. Lanes Lane 1: IL5RA transfected lysate (38.00 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~38 kDa |
| NCBI accession no. | NM_175725.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q01344 |
| General description: | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. (provided by RefSeq) |
| Immunogen: | IL5RA (NP_783852.1, 1 a.a. ~ 335 a.a) full-length human protein. Sequence MIIVAHVLLILLGATEILQADLLPD |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |