Anti-KLRC1 antibody produced in mouse
SIGMA/SAB1406063 - purified immunoglobulin, buffered aqueous solution
Synonym: CD159A; MGC13374; MGC59791; NKG2; NKG2A
Product Type: Chemical
Western Blotting Western Blot analysis of KLRC1 expression in transfected 293T cell line by KLRC1 polyclonal antibody. Lanes Lane 1: KLRC1 transfected lysate (26.30 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~26.3 kDa |
| NCBI accession no. | NM_002259   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P26715 |
| General description: | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. (provided by RefSeq) |
| Immunogen: | KLRC1 (NP_002250.1, 1 a.a. ~ 233 a.a) full-length human protein. Sequence MDNQGVIYSDLNLPPNPKRQQRKPK |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |