Anti-PTPRN2 antibody produced in mouse
SIGMA/SAB1406349 - purified immunoglobulin, buffered aqueous solution
Synonym: IA-2beta; IAR; ICAAR; PTPRP
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of antibody to PTPRN2 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 μg/mL]
Western Blotting PTPRN2 polyclonal antibody. Western Blot analysis of PTPRN2 expression in human kidney.
Western Blotting Western Blot analysis of PTPRN2 expression in transfected 293T cell line by PTPRN2 polyclonal antibody. Lanes Lane 1: PTPRN2 transfected lysate (108.46 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~108.1 kDa |
| NCBI accession no. | NM_130843   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q92932 |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper) |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. (provided by RefSeq) |
| Immunogen: | PTPRN2 (NP_570858.1, 1 a.a. ~ 986 a.a) full-length human protein. Sequence MGPPLPLLLLLLLLLPPRVLPAAPS |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |