Anti-MAP2K4 antibody produced in mouse
SIGMA/SAB1406426 - purified immunoglobulin, buffered aqueous solution
Synonym: JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SEK1; SERK1
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to MAP2K4 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting MAP2K4 polyclonal antibody. Western Blot analysis of MAP2K4 expression in human pancreas.
Western Blotting Western Blot analysis of MAP2K4 expression in transfected 293T cell line by MAP2K4 polyclonal antibody. Lanes Lane 1: MAP2K4 transfected lysate (43.89 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~44.4 kDa |
| NCBI accession no. | BC036032.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | P45985 |
| General description: | This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. (provided by RefSeq) |
| Immunogen: | MAP2K4 (AAH36032.1, 1 a.a. ~ 399 a.a) full-length human protein. Sequence MAAPSPSGGGGSGGGRGSGTPGPVG |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |