Anti-TRIM21 antibody produced in mouse
SIGMA/SAB1406479 - purified immunoglobulin, buffered aqueous solution
Synonym: RNF81; RO52; SSA; SSA1
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to TRIM21 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting TRIM21 polyclonal antibody. Western Blot analysis of TRIM21 expression in A-431.
Western Blotting Western Blot analysis of TRIM21 expression in transfected 293T cell line by TRIM21 polyclonal antibody. Lanes Lane 1: TRIM21 transfected lysate (52.25 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~54.2 kDa |
| NCBI accession no. | NM_003141   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | P19474 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. (provided by RefSeq) |
| Immunogen: | TRIM21 (NP_003132, 1 a.a. ~ 475 a.a) full-length human protein. Sequence MASAARLTMMWEEVTCPICLDPFVE |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |