Anti-STAT5A antibody produced in mouse
SIGMA/SAB1406488 - purified immunoglobulin, buffered aqueous solution
Synonym: MGF; STAT5
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to STAT5A on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting STAT5A polyclonal antibody. Western Blot analysis of STAT5A expression in PC-12.
Western Blotting Western Blot analysis of STAT5A expression in transfected 293T cell line by STAT5A polyclonal antibody. Lanes Lane 1: STAT5A transfected lysate (87.34 kDa). Lane 2: Non-transfected lysate.
Western Blotting STAT5A polyclonal antibody. Western Blot analysis of STAT5A expression in Raw 264.7.
Western Blotting STAT5A polyclonal antibody. Western Blot analysis of STAT5A expression in MCF-7.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~90.6 kDa |
| NCBI accession no. | NM_003152.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, rat, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | P42229 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. (provided by RefSeq) |
| Immunogen: | STAT5A (NP_003143.2, 1 a.a. ~ 794 a.a) full-length human protein. Sequence MAGWIQAQQLQGDALRQMQVLYGQH |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |