Anti-VDR antibody produced in mouse
SIGMA/SAB1406580 - purified immunoglobulin, buffered aqueous solution
Synonym: NR1I1
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to VDR on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of VDR expression in transfected 293T cell line by VDR polyclonal antibody. Lanes Lane 1: VDR transfected lysate (46.97 kDa). Lane 2: Non-transfected lysate.
Western Blotting VDR polyclonal antibody. Western Blot analysis of VDR expression in 293.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~48.3 kDa |
| NCBI accession no. | NM_000376.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | P11473 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein. (provided by RefSeq) |
| Immunogen: | VDR (NP_000367.1, 1 a.a. ~ 427 a.a) full-length human protein. Sequence MEAMAASTSLPDPGDFDRNVPRICG |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |