Anti-WHSC2 antibody produced in mouse
SIGMA/SAB1406594 - purified immunoglobulin, buffered aqueous solution
Synonym: FLJ10442; FLJ25112; NELF-A; NELFA; P/OKcl.15
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to WHSC2 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting WHSC2 polyclonal antibody. Western Blot analysis of WHSC2 expression in Jurkat.
Western Blotting Western Blot analysis of WHSC2 expression in transfected 293T cell line by WHSC2 polyclonal antibody. Lanes Lane 1: WHSC2 transfected lysate (58.08 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 58.08 kDa |
| NCBI accession no. | NM_005663.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| western blot: 1 μg/mL |
| General description: | This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. (provided by RefSeq) |
| Immunogen: | WHSC2 (NP_005654.2, 1 a.a. ~ 528 a.a) full-length human protein. Sequence MASMRESDTGLWLHNKLGATDELWA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |