Anti-NPHS2 antibody produced in mouse
SIGMA/SAB1406635 - purified immunoglobulin, buffered aqueous solution
Synonym: PDCN; SRN1
Product Type: Chemical
Western Blotting NPHS2 polyclonal antibody. Western Blot analysis of NPHS2 expression in human placenta.
Western Blotting Western Blot analysis of NPHS2 expression in transfected 293T cell line by NPHS2 polyclonal antibody. Lanes Lane 1: NPHS2 transfected lysate (34.65 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~34.4 kDa |
| NCBI accession no. | BC029141   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q9NP85 |
| General description: | This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. (provided by RefSeq) |
| Immunogen: | NPHS2 (AAH29141.1, 1 a.a. ~ 315 a.a) full-length human protein. Sequence MERRARSSSRESRGRGGRTPHKENK |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |