Anti-DUSP11 antibody produced in mouse
SIGMA/SAB1406669 - purified immunoglobulin, buffered aqueous solution
Synonym: PIR1
Product Type: Chemical
Western Blotting DUSP11 polyclonal antibody. Western Blot analysis of DUSP11 expression in human kidney.
Western Blotting Western Blot analysis of DUSP11 expression in transfected 293T cell line by DUSP11 polyclonal antibody. Lanes Lane 1: DUSP11 transfected lysate (36.3 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~38.9 kDa |
| NCBI accession no. | NM_003584.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | O75319 |
| General description: | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. (provided by RefSeq) |
| Immunogen: | DUSP11 (NP_003575.1, 1 a.a. ~ 330 a.a) full-length human protein. Sequence MSQWHHPRSGWGRRRDFSGRSSAKK |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |