Anti-SQSTM1 antibody produced in mouse
SIGMA/SAB1406748 - purified immunoglobulin, buffered aqueous solution
Synonym: A170; OSIL; PDB3; ZIP3; p60; p62; p62B
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to SQSTM1 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of SQSTM1 expression in transfected 293T cell line by SQSTM1 polyclonal antibody. Lanes Lane 1: SQSTM1 transfected lysate (48.4 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~47.7 kDa |
| NCBI accession no. | NM_003900   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q13501 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. (provided by RefSeq) |
| Immunogen: | SQSTM1 (NP_003891, 1 a.a. ~ 440 a.a) full-length human protein. Sequence MASLTVKAYLLGKEDAAREIRRFSF |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |