Anti-CLEC10A antibody produced in mouse
SIGMA/SAB1406995 - purified immunoglobulin, buffered aqueous solution
Synonym: CD301; CLECSF13; CLECSF14; HML; HML2
Product Type: Chemical
Western Blotting Western Blot analysis of CLEC10A expression in transfected 293T cell line by CLEC10A polyclonal antibody. Lanes Lane 1: CLEC10A transfected lysate (34.76 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~35.4 kDa |
| NCBI accession no. | NM_182906   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q8IUN9 |
| Application: | Anti-CLEC10A antibody produced in mouse is suitable for western blot assay. |
| Biochem/physiol Actions: | CLEC10A (C-type lectin domain family 10, member A) functions as a tumor associated macrophages in the tumor progression. It has been predicted that after being expressed by macrophages, glycoreceptor CLEC10A may directly interact with the glycan-binding receptors to identify the presence of certain glycan in human tumors. It has also been reported that macrophage cell surface lectin recognizes a common human carcinoma-associated epitope, Tn Ag. |
| General description: | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. (provided by RefSeq) |
| Immunogen: | CLEC10A (NP_878910.1, 1 a.a. ~ 316 a.a) full-length human protein. Sequence MTRTYENFQYLENKVKVQGFKNGPL |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |