Anti-LILRB1 antibody produced in mouse
SIGMA/SAB1407059 - purified immunoglobulin, buffered aqueous solution
Synonym: CD85; CD85J; FLJ37515; ILT2; LIR-1; LIR1; MIR-7; MIR7
Product Type: Chemical
Western Blotting Western Blot analysis of LILRB1 expression in transfected 293T cell line by LILRB1 polyclonal antibody. Lanes Lane 1: LILRB1 transfected lysate (71.5 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~70.8 kDa |
| NCBI accession no. | NM_006669.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q8NHL6 |
| General description: | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) |
| Immunogen: | LILRB1 (AAH15731.1, 1 a.a. ~ 650 a.a) full-length human protein. Sequence MTPILTVLICLGLSLGPRTHVQAGH |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |