Anti-FGF21 antibody produced in mouse
SIGMA/SAB1407309 - purified immunoglobulin, buffered aqueous solution
Product Type: Chemical
Western Blotting FGF21 polyclonal antibody. Western Blot analysis of FGF21 expression in rat brain.
Western Blotting Western Blot analysis of FGF21 expression in transfected 293T cell line by FGF21 polyclonal antibody. Lanes Lane 1: FGF21 transfected lysate (22.99 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~22.3 kDa |
| NCBI accession no. | BC018404   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q9NSA1 |
| Biochem/physiol Actions: | The members of FGF (fibroblast growth factor) family take part in cell survival and mitogenic activities. FGFs are associated with a number of physiological processes such as cell growth, morphogenesis, embryonic development, tissue repair, tumor growth and invasion. FGF21 is a hormonal factor that regulates glucose homeostasis and energy metabolism. It possesses anti-diabetic properties by mediating glucose uptake in peripheral tissues. It also exhibits autocrine effects in white adipose tissue. FGF21 is present in milk and is needed for intestinal function in the neonate. It is also associated with bone loss. FGF21 is considered hepatoprotective in nature. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | FGF (fibroblast growth factor) family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. The gene is mapped to human chromosome 19q13.33 and codes for a member of FGF superfamily. The encoded protein is produced in liver. |
| Immunogen: | FGF21 (AAH18404.1, 1 a.a. ~ 209 a.a) full-length human protein. Sequence MDSDETGFEHSGLWVSVLAGLLLGA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |