Anti-GPR77 antibody produced in mouse
SIGMA/SAB1407342 - purified immunoglobulin, buffered aqueous solution
Synonym: C5L2; GPF77
Product Type: Chemical
Western Blotting Western Blot analysis of GPR77 expression in transfected 293T cell line by GPR77 polyclonal antibody. Lanes Lane 1: GPR77 transfected lysate (37.07 kDa). Lane 2: Non-transfected lysate.
Flow Cytometry FACS analysis of negative control 293 cells (Black) and GPR77 expressing 293 cells (Green) using GPR77 purified mouse polyclonal antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~36.1 kDa |
| NCBI accession no. | NM_018485.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: suitable |
| western blot: 1 μg/mL |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).[supplied by OMIM |
| Immunogen: | GPR77 (NP_060955.1, 1 a.a. ~ 337 a.a) full-length human protein. Sequence MGNDSVSYEYGDYSDLSDRPVDCLD |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |