Anti-VENTX antibody produced in mouse
SIGMA/SAB1407352 - purified immunoglobulin, buffered aqueous solution
Synonym: HPX42B; MGC119910; MGC119911; NA88A; VENTX2
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to VENTX on HepG2 cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of VENTX expression in transfected 293T cell line by VENTX polyclonal antibody. Lanes Lane 1: VENTX transfected lysate (28.38 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~27.6 kDa |
| NCBI accession no. | NM_014468.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | O95231 |
| Biochem/physiol Actions: | Vent homeobox(VENTX) regulates proliferation and differentiation of hematopoietic cells.VENTX acts as a tumor suppressor and plays an important role in proinflammatory activation.Dysregulation of VENTX may contribute to pathogenesis of autoimmune diseases. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas (provided by RefSeq). Vent homeobox (VENTX) is a human homeobox transcription factor. VENTX is majorly expressed in human myeloid cells. VENTX gene is located on human chromosome 10q26.3. |
| Immunogen: | VENTX (NP_055283.1, 1 a.a. ~ 258 a.a) full-length human protein. Sequence MRLSSSPPRGPQQLSSFGSVDWLSQ |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |