Anti-FBXW5 antibody produced in mouse
SIGMA/SAB1407546 - purified immunoglobulin, buffered aqueous solution
Synonym: DKFZp434B205; Fbw5; MGC20962; RP11-229P13.10
Product Type: Chemical
Western Blotting Western Blot analysis of FBXW5 expression in transfected 293T cell line by FBXW5 polyclonal antibody. Lanes Lane 1: FBXW5 transfected lysate (17.49 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~18.5 kDa |
| NCBI accession no. | BC000850.1   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q969U6 |
| General description: | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. (provided by RefSeq) |
| Immunogen: | FBXW5 (AAH00850.1, 1 a.a. ~ 159 a.a) full-length human protein. Sequence MGLSPDNRYLYVNSRAWPNGAVVAD |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |