Anti-TNS4 antibody produced in mouse
SIGMA/SAB1408140 - purified immunoglobulin, buffered aqueous solution
Synonym: CTEN; FLJ14950; PP14434
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to TNS4 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of TNS4 expression in transfected 293T cell line by TNS4 polyclonal antibody. Lanes Lane 1: TNS4 transfected lysate (52.8 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~51.8 kDa |
| NCBI accession no. | BC018706   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q8IZW8 |
| Application: | Anti-TNS4 antibody produced in mouse is suitable for indirect immunofluorescence and western blot. |
| Biochem/physiol Actions: | TNS4 (Tensin 4) is mainly involved in cell migration activity. It exhibits oncogenic property in colonic, breast, lung, and gastric cancers. In studies, its overexpression has been reported in the pancreatic cancer cells. In pancreatic cancer cells, TNS4 promotes colony formation and cell motility. It has been predicted that TNS4 could be a prognostic marker for primary melanoma. |
| General description: | Mouse polyclonal antibody raised against a full-length human TNS4 protein. |
| General description: | TNS4 (Tensin 4) is a signaling molecule localized in the prostate and placenta. It is a member of the TENSIN gene family. It has a Src homology 2 and phosphotyrosine-binding domains. Its expression has been observed in the early progression of melanoma cells. |
| Immunogen: | TNS4 (AAH18706.1, 1 a.a. ~ 480 a.a) full-length human protein. Sequence MGSKASSPHGLGSPLVASPRLEKRL |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |