Anti-HFE2 antibody produced in mouse
SIGMA/SAB1408376 - purified immunoglobulin, buffered aqueous solution
Synonym: HFE2A; HJV; JH; MGC23953; RGMC
Product Type: Chemical
Western Blotting Western Blot analysis of HFE2 expression in transfected 293T cell line by HFE2 polyclonal antibody. Lanes Lane 1: HFE2 transfected lysate (34.43 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen ~33.7 kDa |
| NCBI accession no. | NM_145277.3   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q6ZVN8 |
| General description: | The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. (provided by RefSeq) |
| Immunogen: | HFE2 (NP_660320.3, 1 a.a. ~ 313 a.a) full-length human protein. Sequence MIQHNCSRQGPTAPPPPRGPALPGA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |