Anti-TMEM123 antibody produced in mouse
SIGMA/SAB1408843 - purified immunoglobulin, buffered aqueous solution
Synonym: KCT3; PORIMIN; PORMIN
Product Type: Chemical
Western Blotting Western Blot analysis of TMEM123 expression in transfected 293T cell line by TMEM123 polyclonal antibody. Lanes Lane 1: TMEM123 transfected lysate (22.88 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 21.5 kDa |
| NCBI accession no. | NM_052932.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | Q8N131 |
| General description: | This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. (provided by RefSeq) |
| Immunogen: | TMEM123 (NP_443164.2, 1 a.a. ~ 208 a.a) full-length human protein. Sequence MGLGARGAWAALLLGTLQVLALLGA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |